【Master Lecture】September 27, 2019, Friday
Topic: Multiscale Molecular Simulation
Date: SEP 27, 2019 (Fri)
Time: 09:30-10:30
Venue: Governing Board Meeting Room of Dao Yuan Building
Language: English
Origin:
Since the establishment of the Warshel Institute in 2017, Prof. Arieh Warshel has visited CUHK- Shenzhen many times to assist in the construction of the institute and to give many academic sharing instructions. This Master Forum is honored to invite him to come again and hopes to deepen the exchanges and cooperation between the school and the laboratory of Prof. Warshel of the University of Southern California from the professor's lecture. Therefore, Prof. Warshel will lead his postdoc fellow to give more communication to the teachers and students. After the Forum, Prof. Warshel will have an interactive discussion with the LHS undergraduate students and the Nobel Prize class at the original place.
Speaker Profile:
Professor Prof. Arieh Warshel is a Distinguished Professor of Chemistry and Biochemistry and holds the Dana and David Dornsife Chair in Chemistry at the University of Southern California. The multi-scale molecular simulation method developed by Prof. Warshel has been successfully applied to biomolecular systems and protein reaction mechanisms, and thus won the 2013 Nobel Prize in Chemistry. Prof. Warshel has published 390 research papers and a book published in the 1991 book "Computer Models for Chemical Reactions in Enzymes and Solvents." Prof. Warshel is also an academician of the National Academy of Sciences and an honorary member of the Royal Society of Chemistry. He has won several awards, such as the Tolman Medal in 2003, the Royal Society of Soft Materials and Biophysical Chemistry in 2012, and the 2014 Founders Award of the Biophysical Society.
Abstract:
In recent decades, people's understanding of human health at the molecular level has made tremendous progress. However, little is known about the relationship between protein structure and sequence and the function of the corresponding protein. The above research process can be significantly accelerated by multi-scale computer simulation of high complexity and multi-system. Multi-scale computer simulation is currently applied to systems related to critical medical problems, including enzyme design, drug resistance, and proton and ion transport mechanisms to clarify the basics of catalytic control, bioenergy, energy transduction in living systems mechanism.
